NAME Ying-Hen Hsieh
POSITION Professor
PHONE 04-22053366 # 6109
WEBSITE http://mail.cmu.edu.tw/~hsieh/
E-MAIL hsieh@mail.cmu.edu.tw
EDUCATION

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1.International School, Bangkok, 1967-1972

2.Baldwin-Wallace College, B.S. (magna cum laude), Mathematics, 1972-1976.

3.Carnegie-Mellon University, M.S., Mathematics, 1976-1978.

4.Carnegie-Mellon University, Ph.D., Applied Mathematics, 1978-1982. Supervisor: Dr. Bernard D. Coleman. Thesis Title: Demographic Prediction under Varying Vital Statistics.
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ACADEMIC POSITIONS

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1.Teaching Assistant, Department of Mathematics, Carnegie Mellon University, 1976-1982.

2.Associate Professor, National Chung Hsing University, 1982-87.

3.Professor, National Chung Hsing University, 1987-present.

4.Chairman and Professor, Department of Applied Mathematics, National Chung Hsing University, 1995-97.

5.Adjunct Professor, Institute of Mathematical Modeling and Scientific Computing, National Chiao Tung University, 2006-.

6. Professor, Department of Public Health and Biostatistics Center, China Medical University, 2007-.

7.Adjunct Professor, Department of Applied Mathematics, National Chung Hsing University, 2007-.

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VISITING ACADEMIC POSITIONS

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1.1991-1992, Visiting Scientist, Center of Applied Mathematics, Cornell University.

2.Spring 1992, Visiting Professor, Department of Mathematics, Harvey Mudd College.

3.Summer 1996, Visiting Professor, Department of Mathematics, University of Memphis.

4.1997-1998, Visiting Scientist, Wellcome Centre for the Epidemiology of Infectious Diseases, Oxford University.

5.Summer 1998, Visiting Professor, Department of Mathematics, University of Memphis.

6.Fall 2002, Visiting Scientist, Biomathematics Department, UCLA, Los Angeles USA

7.Fall 2006, Visiting Professor, Department of Mathematics, University of New South Wales, Sydney, Australia 

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OTHER SHORT ACADEMIC VISITS

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1.      ICTP, Trieste, Italy, October 1988

2.     University of Montreal, Montreal, Canada, June 1992.

3.      Chulalongkorn University, Bangkok, Thailand, February 2001

4.      Ministry of Public Health, Thailand, February 2001

5.      LaTrobe University, LaTrobe, Australia, February 2002

6.      Université René Descartes (Paris V), Paris, France, July 2002

7.      Université René Descartes (Paris V), Paris, France, July 2002

8.      US CDC, Atlanta, USA, January 2005

9.      Vanderbilt University, Nashville, USA, February 2005

10.      Université René Descartes (Paris V), Paris, France, July 2005

11.      University of Victoria, Victoria, Canada, July 2005.

12.      University of British Columbia, Vancouver, Canada, August 2005.

13.      IMS, National Singapore University, Singapore, September, 2005.

14.      Harbin Institute of Technology, Harbin, China, July, 2007.

15.    Northeast Normal University, Department of Mathematics, Changchun, China, July.

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RESEARCH INTERESTS


Mathematical Biology, Mathematical and Statistical Modeling of Infectious Diseases Epidemiology, Ordinary Differential Equations, Population Dynamics, Mathematical Ecology

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COURSES TAUGHT


Undergraduate Courses:
Calculus (for math majors as well as for engineering, biological, agricultural, and life sciences students), Ordinary Differential Equations, Linear Algebra, Partial Differential Equations, Vector Analysis, engineering mathematics, Computational Linear Algebra (for non-math majors), Linear Programming, Numerical Analysis,

Graduate Courses: Methods of Applied Mathematics (for graduate students in mathematics, engineering, and theoretical mechanics), Qualitative Theory of Ordinary Differential Equations, Advanced Topics in Ordinary Differential Equations (including applications to population dynamics and biomathematics), and graduate seminars at medical and public health schools on mathematical modeling in infectious disease epidemiology.

         Supervised Student Thesis:

1.      Shen-Mu Tsai, Master in Applied Mathematics, 1995

2.      Chien-Hsun Chen, Master in Applied Mathematics, 2000

3.      Yun-Shi Wang, Master in Applied Mathematics, 2005

4.      Yuan-Sen Cheng, Master in Applied Mathematics, 2005

5.      Chin-Kuei Shiao, Master in Applied Mathematics, 2006

        Currently supervised students:

Yun-Shi Wang, Ph.D. student

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HONORS AND AWARDS

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1.      National Honor Society, International School, Bangkok, 1971.

2.      Rotary International Scholarship, Baldwin-Wallace College, 1972-76.

3.      Mathematics Honorary, Baldwin-Wallace College, 1974.

4.      Loomis Mathematics Prize, Baldwin-Wallace College, 1975.

5.      Rotary International Student Award, Baldwin-Wallace College, 1975.

6.      Graduate Teaching Fellowship, Carnegie-Mellon University, 1976-1982.

7.      National Science Council (ROC) Annual Research Award, 1984-94, 1997, 2000. (discontinued after 2000)

8.      Marquis Who¡¦s Who 1995, Marquis Who¡¦s Who in Health and Medicine 2002

9.      2005 Canadian Studies Faculty Research Award

10.      2006 National Chung Hsing University Faculty Outstanding Research Award

11.      National Science Council (ROC) Level 1 PI¡¦s stipend, 2005, 2006

12.     China Medical University, Faculty Outstanding Research Award, 2007-2010.

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SERVICE AND OTHER POSITIONS HELD

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1.      Member of Executive Board, National Union of University Reforms, Taiwan, 1991-92.

2.     Chairman of Executive Board, National Chung Hsing University Faculty Association, 1993-1995.

3.     Member of National Chung Hsing University President Selection Committee, National Chung Hsing University, 1994, 1997, 2001.

4.     Member of National Chung Hsing University, College of Science, and Department of Applied Mathematics Academic Committee and Faculty Evaluation Committee, several terms.

5.  Board member, World Outreach Council, Society for Mathematical Biology, 1998-present

6.     Member, Center for Promotion of Mathematics Committee, National Science Council of Taiwan, 2001-2004

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PUBLICATIONS

(* denotes correspondence author)                                                                                              Update: 2008/10/13

1. Coleman, B.D. and Hsieh, Y.-H. (1979) Theory of the dependence of population levels on environmental history for semelparous species with short reproductive seasons. Proc. Natl. Acad. Sci. USA; 76(10): 5407-5410. (SCI: Proc. Natl. Acad. Sci. USA) PDF

2. Coleman, B.D., Hsieh, Y.-H. and Knowles, G.P. (1979) On the optimal choice of r for a population in a periodical environment. Math. Biosci; 45: 159-173. (SCI: Math. Biosci)

3. Coleman, B.D., Mares, M.A., Willig, M.R. and Hsieh, Y.-H. (1982) Randomness, Area, and species richness. Ecology; 63(4): 1121-1133. (SCI: Ecology) PDF

4. Hsieh, Y.-H. (1985) On the use of optimal estimate in demography. J. Sci. Eng. NCHU; 22: 211-226.

5. Hsieh, Y.-H. (1986) A periodical population model. Proc. Natl. Sci. Council, ROC; 10(3): 266-274. PDF

6. Hsieh, Y.-H. (1986) On density-dependent models and periodical populations, J. Sci. Eng. NCHU; 23: 123-132.

7. Coleman, B.D. and Hsieh, Y.-H.* (1986) On species-area relations: I. Random placement and sampling average. Soochow J. Math.; 12: 11-22. (SCI: Soochow J. Math)

8. Coleman, B.D. and Hsieh, Y.-H.* (1987) On species-area relations: II. Estimates of abundance data. Soochow J. Math.; 13(1): 31-44. (SCI: Soochow J. Math)

9. Hsieh, Y.-H. (1988) The phenomenon of unstable oscillation in population models. Math. Comput. Modeling; 10(6): 429-435. (SCI: Math. Comput. Modeling)

10. Hsieh, Y.-H. (1989) On the evolution of altruism in an age-structured population. Math. Comput. Modeling; 11: 427-475. (SCI: Math. Comput. Modeling)

11. Hsieh, Y.-H. (1990) An AIDS model with screening. Math. Comp. Mod.; 14: 640-643. (SCI: Math. Comp. Mod)

12. Hsieh, Y.-H. (1990) Evolution of altruism communities. COENOSES; 4(3): 145-147. PDF

13. Hsieh, Y.-H. (1991) Persistence of altruistic community under indiscriminate altruism. Proc. NSC(ROC); 15(1): 33-39. PDF

14. Hsieh, Y.-H. (1991) Modelling the effect of screening in HIV transmission dynamics. Differential Equations Models in Biology, Epiemiology and Ecology, Proc. Inter. Conf. on Diff. Eq. Claremont, Lec. Notes in Biomath., pp. 99-120. Springer-Verlag, New York. 

15. Hsieh, Y.-H. (1991) An altruistic population model with sex differences. Mathematical Population Dynamcis, Proc. 2nd Inter. Conf. Math. Popula. Dynamics. (O. Arino, D. Axelrod and M. Kimmel, eds.) Lecture Notes in Pure and Applied Mathematics, pp. 63-73. Marcel Dekker, Inc. New York. PDF

16. Hsieh, Y.-H. (1992) Optimal estimate of population structure under varying vital rates. Math. Popu. Studies; 3(4): 289-299. PDF

17. Velaso-Hernanadez, J.X. and Hsieh, Y.-H. (1994) Modeling the effect of treatment and behavioral change in HIV transmission dynamics. J. Math. Biol.; 32: 233-429. (SCI: Misc. Mathematics, Misc. Biology) PDF

18. Hsieh, Y.-H. and Velaso-Hernanadez, J. (1995) Community treatment of HIV-1: Initial and asymptotic dynamics. BioSystems; 35(1): 75-81. (SCI: Biology) PDF

19. Busenberg, S., Cooke, K., and Hsieh, Y.-H. (1995) A model for HIV in Asia. Math. Biosci.; 128(12): 185-210. (SCI: Misc. Mathematics, Misc. Biology) PDF

20. Hsieh, Y.-H. (1996) A two-sex model for treatment of HIV and behavior change in a population of varying size. IMA J. Math. Appl. Med. Biol.; 13: 151-173. (SCI: Misc. Mathematics, Misc. Biology) PDF

21. Chen, C.W.S., Lee, S.-M., Hsieh, Y.-H., and Ungchusak, K. (1999) A unified approach to estimating population size for births only models. Compu. Stat. Data Analysis; 32: 29-46. (SCI: Statistics) PDF

22. Hsieh, Y.-H.* and Cooke, K. (2000) Behavior Change and Treatment of Core Group and Bridge Population: Its Effect on the Spread of HIV/AIDS. IMA J. of Math. Appl. Biol. Med.; 17(3): 213-241. (SCI: Mics. Mathematics, Misc. Biology) PDF

23. Hsieh, Y.-H.*, Chen, C.W.S., and Lee, S-M. (2000) Empirical Bayes approach to estimating the number of HIV-infected individuals in hidden and elusive populations. Stat. Med.; 19: 3095-3108. (SCI: Statistics, Public Health) PDF

24. Hsieh, Y.-H.*, Lee, S.-M., Chen, C.W.S., and Arazoza, H. (2001) On the recent sharp increase of HIV infections in Cuba. AIDS.; 13(3): 425-428 (SCI: Public Health, Infectious Diseases) PDF

25. Hsieh, Y.-H.* and Hsu, S.-P. (2001) The effect of density-dependent treatment/behavior change on the transmission dynamics of HIV. J. of Math. Biol.; 43: 69-80. (SCI) PDF

26. Hsieh, Y.-H.*, Arazoza, H., Lee, S.-M., and Chen, C.W.S. (2002) Estimating the number of HIV-infected Cubans by sexual contact. Int. J. of Epidemiology; 31: 679-683. (SCI: Public Health) PDF

27. Hsieh, Y.-H. (2002) The changing faces of commercial sex in Thailand: its implications for HIV transmission. JAIDS.; 30(5): 537-540. (SCI: Public Health) PDF

28. Hsieh, Y.-H. (2003) Politics hindering SARS work. Nature; 423: 381, May 22, 2003. (SCI: Multidisciplinary Sciences) PDF

29. Hsieh, Y,-H.* and Chen, C.W.S. (2003) Severe Acute Respiratory Syndrome: Numbers do not tell whole story. British Med. Journal; 326: 1395-1396, June 21, 2003. (SCI: Medicine, General and Internal) PDF

30. Hsieh, Y.-H. (2003) SARS and the Internet. New Eng. J Medicine; 349(7): 711-2, August 14, 2003 (SCI: Medicine, General and Internal) PDF

31. Hsieh Ying-Hen*, Cathy W.S. Chen. (2003) Re: Mathematical modeling of SARS: Cautious in all our movements. J Epidem Com Health (18 November 2003). Available at http://jech.bmjjournals.com/cgi/eletters/57/6/DC1#66. (SCI: Public Health) PDF

32. Li, C.-S., Liang, H. Hsieh, Y.-H., and Twu, S-J. (2003) Comparison of viral trajectories in AIDS Studies using nonparametric mixed-effects models. Journal of Modern Applied Statistical Methods; 2(2):443-450. PDF

33. Hsieh, Y.-H.* and Chen, C.H. (2004) Modeling the social dynamics of the sex industry in Thailand: Its implications for spread of HIV. Bull. Math. Biol.; 66(1): 143-166. (SCI: Mathematics, Interdisciplinary applications).PDF

34. Hsieh, Y.-H.* C.W-S. Chen and S.-B. Hsu. (2004) SARS outbreak, Taiwan 2003. Emerging Infectious Diseases; 10(2):201-206. Available online at: http://www.cdc.gov/ncidod/eid/vol10no2/03-0515.htm. (SCI: Infectious Diseases) PDF

35. Hsieh, Y.-H.* J-Y Lee and H.L. Chang. (2004) SARS epidemiology, logistic-type model, and cumulative case number. Emerging Infectious Diseases; 10(6):1165-7, June 2004. (SCI: Infectious Diseases) PDF

36. Hsieh Y,-H.*, Chen CWS, Hsu SB. (2004) SARS outbreak in Taiwan (reply to Hsueh and Yang). Emerging Infectious diseases; 10(8):1515-6, August 2004. (SCI: Infectious Diseases) PDF

37. Hsieh, Y.-H.*, Chen, CWS. (2004) Mathematical modeling of SARS: Errata and updates. J Epidem Com Health, published online May 11, 2004. Available at: http://jech.bmjjournals.com/cgi/eletters/57/6/DC1. (SCI: Public Health) PDF

38. Hsieh, Y.-H. (2004) If we ignore politics, will politics ignore science? Nature; 432: 671. (SCI: Multidisciplinary Sciences) PDF

39. Hsieh, Y.-H.*, de Arazoza Rodríguez, Héctor, Rachid Lounes. (2005) A Class of Models for HIV Contact Tracing in Cuba: Implications for Intervention and Treatment. To appear in "Deterministic and Stochastic Models for AIDS Epidemics and HIV Infection with Interventions." (Ed. W.Y. Tan). Singapore: World Scientific. Preprint

40. Hsieh Y.-H.*, King CC, Ho MS, Chen CWS, Lee JY, Liu FC, Wu YC, Wu JSJ. (2005) Quarantine for SARS, Taiwan. Emerging Infectious Diseases; 11(2):278-82. (SCI: Infectious Diseases) PDF

41. Hsieh, Y.-H. (2005) Despite some flaws, online submission is the future. Nature; 435: 1160. (SCI: Multidisciplinary Sciences) PDF

42. Hsieh Y.-H. (2005) Mapping the complexities of science and politics. Nature; 438: 24. (3 November 2005) PDF

43. Hsieh, Y.-H.*, H.-C. Wang, H. de Arazoza, R. Lounes, S-.J. Twu, and H.-S. Hsu. (2005) Ascertaining HIV underreporting in low HIV prevalence settings. J. Biol. Systems; 13(4): 441-454. (SCI: Mathematics, Interdisciplinary applications) Preprint

44. Hsieh Y.-H.* and Y. S. Cheng. (2006) Real-time forecast of multi-wave epidemic outbreaks. Emerging Infectious Diseases; 12(1):122-7. (SCI: Infectious Diseases).  PDF

45. Chen, C.W.S. and Hsieh, Y.-H. (2006) Bias may be unintentional but it's still there. Nature; 439:18.PDF

46. S.B. Hsu and Hsieh Y.-H.* (2006) Modeling intervention measures and public response during SARS outbreak. SIAM J. Appl Math; 66(2): 627-647. (SCI: Applied Mathematics) PDF

47. Hsieh, Y.-H.* and Y.-S. Wang. (2006) Basic reproduction number HIV model incorporating commercial sex and behavior change. Bull. Math. Biol.; 68: 551¡V575. (SCI: Mathematics, Interdisciplinary applications) PDF

48. Hsieh, Y.-H.*, S.M. Lee, C.W.S. Chen, Y.M. Chen, S.I. Wu, S.F. Lai, and A.L. Chang. (2006) Estimating the HIV-infected population size in hard-to-count populations: the case of gay sauna patrons in Taipei. Physica A ; 362(2): 495-503. (SCI: Physics, Multidisciplinary) PDF

49. P. Georgescu and Y.-H. Hsieh*. (2006) Global Stability for a Virus Dynamics Model with Nonlinear Incidence of Infection and Removal. SIAM J. Applied Mathematics; 67(2): 337-353. (SCI: Applied Mathematics) PDF

50. Hsieh Y.-H.*, C.C. King, C.W.S. Chen, M.S. Ho, S.B. Hsu, and YC Wu. (2007) Impact of Quarantine on the 2003 SARS Outbreak: a retrospective modeling study. J. Theoretical Biology; 244: 729-736. (SCI: Biology) PDF

51. Y.-H. Hsieh, P. van den Driessche, and L. Wang. (2007) A multi-patch model for spatial spread of disease: Impact of Travel between patches. Bull. Math. Biology; 69(4): 1355-75. (SCI: Mathematics, Interdisciplinary applications) PDF

52. Paul S.F. Yip, Y.-H. Hsieh, Tina Y. Xu, K.F. Lam, C. C. King, and H. L. Chang. (2007) Assessment of Intervention Measures for the 2003 SARS Epidemic in Taiwan by Use of a Back-Projection Method. Infect Control Hosp Epidemiol; 28(5): 525-530. (SCI: Public, Environmental, and Occupational Health) PDF

53. P. Georgescu and Y.-H. Hsieh*. (2007) Global Dynamics of a Predator-prey Model with Stage Structure for Predator. SIAM J. Applied Mathematics; 67(5): 1379-1395. (SCI: Applied Mathematics) PDF

54. Hsieh Y.-H. (2008) Richards Model: A Simple Procedure for Real-time Prediction of outbreak Severity. To appear in Modeling and Dynamics of Infectious Diseases. Zhien Ma Jianhong Wu, Yicang Zhou, eds. Series in Contemporary Applied Mathematics (CAM), Vol. 11, 2008.9, Beijing, Higher Education Press. PDF

55. S.B. Hsu and Hsieh Y.-H.* (2008) On the Role of Asymptomatic Infection in Transmission Dynamics of Infectious Diseases. Bull. Math. Biology; 70: 134-155. (SCI: Mathematics, Interdisciplinary applications) PDF

56. R. Lounes, H. de Arazoza, Y-H. Hsieh and J. Joanes. (2008) Deterministic modeling of the size of the HIV/AIDS epidemic in Cuba. In ¡§Parametric Mathematical Methods in Survival Analysis, Reliability and Quality of Life¡¨, C. Huber, N. Limnios, M. Mesbah, M. Nikulin (Editors), Hermes (ISTE), J. Wiley.

57.  Hsieh Y.-H.* and Chin-Kuei Hsiao. (2008) Predator-prey Model with Disease Infection in Both Populations,  Mathematical Medicine and Biology; 25(3): 247-266. (SCI: Biology) PDF  

58.  Hsieh Y.-H.* and Stefan Ma. Intervention Measures, Turning Point, and Reproduction Number for Dengue, Singapore, 2005. Am. J. Trop. Med. Hyg. Accepted. (SCI impact factor: 2.183, Tropical Medicine; 3/14) PDF 

59. C. Sun and Y.-H. Hsieh. Global analysis for SEIR model with vaccination. Submitted.

60. T.C. Li, Y.-H. Hsieh*, S.-J. Twu, and H.-M. Hsu. Survival and Progression to AIDS: Analysis of the Efficacy of Highly Active Antiretroviral Therapy in Taiwan. Submitted.

61.  Eric Ho Yin Lau, Chwan Chuan King, Wenhu Chang, Ying Hen Hsieh, et al. Standardized Case Fatality Rates for Severe Acute Respiratory Syndrome (SARS) in Beijing, Hong Kong, and Taiwan Adjusted for Age, Gender, and Healthcare Workers. Submitted.

62. Hsieh Y.-H.*, F. Brauer. Swift implementation of culling to contain animal-to-human avian flu outbreak. Submitted.

63. Yi-Kuan Tseng and Ying-Hen Hsieh*. A Joint Model Approach for Evaluating the Efficacy of HAART for AIDS

      patients via Association between CD4 Count and Survival Time. Under revision.

64.  M.S. Ho, Y.-H. Hsieh, S.-F. Hsu-Schmitz, C.W.S. Chen, C.C. King, W.J. Chen, and H.-L. Chang. Candidate genes associated with susceptibility to SARS-CoV. Manuscript in preparation.

65. Y.-H. Hsieh, G. Webb, and J. Wu. Impact of Pre-symptomatic Influenza Transmission on Pandemic Influenza.Manuscript in preparation.

66. Y.-H. Hsieh. Turning Points and Impact of Climate on Two-Wave Dengue Outbreak in Taiwan, 2007, Manuscript in preparation.

RESEARCH GRANTSNTSS

l   Chief investigator of 28 consecutive National Science Council of Taiwan (NSC) Research Grants from 1982 to 2011.

l   Co-investigator of Fogarty International Center/NIH Grant (1R03 TW00536-01) from 1996-1998 (3 years).

l   Co-investigator of CDC of Taiwan Research Grant 2001.

l   Chief investigator of CDC of Taiwan Research Grants 2002-2003 (2 years).

l   Chief investigator of National Science Council of Taiwan (NSC) SARS Research Grants, 2003-2005 (2 years).

l   Chief investigator of Taiwan Pandemic Influenza Vaccination R&D Program Grants (Taiwan CDC) 2006-2007 (1.5 years).

Grants awarded 2004-2008 (Grant budget in NT dollars):

Grant

Role

Duration

Budget

Source

      NSC-92-2751-B-005-001-Y

PI

2003/07/01-

    2004/06/30

706,600

NSC

      NSC-92-2125-M-005-002

PI

2003/08/01-

    2004/07/31

581,100

 

NSC

      NSC-93-2751-B-005-001-Y

PI

2004/07/01-

    2005/06/30

700,000

NSC

      NSC-93-2125-M-005-001

PI

2004/08/01-

    2005/07/31

550,000

 

NSC

      NSC-94-2125M-005-006

PI

2005/08/01-

    2006/07/31

714,000

NSC

      NSC-94-2314-B-005-002

PI

2005/08/01-

   2006/07/31

742,000

NSC

      DOH95-DC-1407

PI

2006/01/01-

2007/7/31

1,759,275

CDC-Taiwan

      Epidemiological Modeling of HIV infection in Cuba (with R. Lounes and H. de Arazoza)

Co-PI

2004-2007

2,345,500

      Ministere délégué de la Recherche (French Ministry Delegated to Research)

      NSC-95-2115-M-005-003

PI

2006/08/01-

    2007/07/31

740,000

NSC

      NSC-96-2115-M-039-002

PI

2007/08/01-

    2008/07/31

585,000